I bring the largest suitcase allowed on Southwest, packed just to under 50 pounds and include a soft extra bag that is empty on the outward trip but may be full on the way back.
On the airplane I'll have a very small carryon, my sleep apnea machine and my computer in case.
Now I have to think about buses and rolling from casino to casino.
So at arrival after weight is no longer an issue, all or most of my carryons go into the large bag to make for an easy roll. However, it is heavy getting into the bus.
Sometimes I collect some things to bring home, especially decks of cards for home poker games. Or I might win some prize. These add weight. So then the soft bag works to divide up the stuff on the way home and keep the weight of the large bag under 50 pounds. It also is protection against overpacking on the way out where I don't have a scale right in my hotel room as I do at home.
I weigh at the airport and if my large bag is over 50 pounds, I repack.
Whereas in Vegas I needed to get down to just one suitcase, at my home airport with help from whomever picks me up, I can easily manage two.
I'm looking at Eastside Cannery next trip as a middle stay for a good wash of laundry, but I pack very light shirts that dry easily and I wash in the room every couple days. I like jeans, but light shirts or shorts are more practical as they dry efficiently. I bring as many socks as I can manage. I hate socks washed in the room. Socks fit in all the little spaces and actually are good protection in the computer bag or sleep apnea bag